Portraying the dark side of endogenous IFN-λ for promoting cancer progression and immunoevasion in pan-cancer

Abstract Background IFN-λ has been shown to have a dual function in cancer, with its tumor-suppressive roles being well-established. However, the potential existence of a negative ‘‘tumor-promoting’’ effect of endogenous IFN-λ is still not fully understood. Methods We conducted a comprehensive revie...

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Autori principali:	Zhen Zhen Wang, Xiao Ling Wen, Na Wang, Xu Hua Li, Yu Guo, Xu Zhu, Shu Heng Fu, Fei Fan Xiong, Jin Li, Limei Wang, Xiao Ling Gao, Hong Jiu Wang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2023-09-01
Serie:	Journal of Translational Medicine
Soggetti:	Endogenous IFN-λ Cancer-promoting Multi-omics Tumor microenviroment Copy number variation
Accesso online:	https://doi.org/10.1186/s12967-023-04453-4
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