USP29 Deubiquitinates SETD8 and Regulates DNA Damage-Induced H4K20 Monomethylation and 53BP1 Focus Formation

SETD8 is a histone methyltransferase that plays pivotal roles in several cellular functions, including transcriptional regulation, cell cycle progression, and genome maintenance. SETD8 regulates the recruitment of 53BP1 to sites of DNA damage by controlling histone H4K20 methylation. Moreover, SETD8...

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Autori principali:	Yeray Hernández-Reyes, María Cristina Paz-Cabrera, Raimundo Freire, Veronique A. J. Smits
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-08-01
Serie:	Cells
Soggetti:	SetD8/Set8/PR-Set7/KMT5A USP29 53BP1 H4K20me DNA damage response histone methylation
Accesso online:	https://www.mdpi.com/2073-4409/11/16/2492
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