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USP29 Deubiquitinates SETD8 and Regulates DNA Damage-Induced H4K20 Monomethylation and 53BP1 Focus Formation

SETD8 is a histone methyltransferase that plays pivotal roles in several cellular functions, including transcriptional regulation, cell cycle progression, and genome maintenance. SETD8 regulates the recruitment of 53BP1 to sites of DNA damage by controlling histone H4K20 methylation. Moreover, SETD8...

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שמור ב:
Principais autores: Yeray Hernández-Reyes, María Cristina Paz-Cabrera, Raimundo Freire, Veronique A. J. Smits
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2022-08-01
סדרה:Cells
נושאים:
SetD8/Set8/PR-Set7/KMT5A
USP29
53BP1
H4K20me
DNA damage response
histone methylation
גישה מקוונת:https://www.mdpi.com/2073-4409/11/16/2492
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