Epitope analysis and protection by a ROP19 DNA vaccine against Toxoplasma gondii

We used bioinformatics approaches to identify B-cell and T-cell epitopes on the ROP19 protein of Toxoplasma gondii. Then, we constructed plasmids with ROP19 (pEGFP-C1-ROP19) and injected them into BALB/c mice to test the immunoprotection induced by this vaccine candidate. The results showed that imm...

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Dettagli Bibliografici

Autori principali:	Zhou Jian, Wang Lin, Lu Gang, Zhou Aihua, Zhu Meiyan, Li Qihang, Wang Zhilin, Arken Miradel, Wang Ao, He Shenyi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	EDP Sciences 2016-01-01
Serie:	Parasite
Soggetti:	DNA vaccine Immunity ROP19 Toxoplasma gondii BALB/c mice
Accesso online:	http://dx.doi.org/10.1051/parasite/2016017
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