Adjuvantic cytokine IL-33 improves the protective immunity of cocktailed DNA vaccine of ROP5 and ROP18 against toxoplasma gondii infection in mice

Toxoplasma gondii is a threat for immunocompromized individuals, and no treatment is available for enhancing immunity against infection. Molecular adjuvants may improve the efficacy of DNA vaccine-induced T cell immunity. Here, we report that cocktailed DNA immunization with ROP5 and ROP18 boosted i...

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Bibliografische Detailangaben

Hauptverfasser:	Zhu Yu-Chao, He Yong, Liu Jian-Fa, Chen Jia
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	EDP Sciences 2020-01-01
Schriftenreihe:	Parasite
Schlagworte:	toxoplasma gondii toxoplasmosis il-33 rhoptry protein 5 (rop5) rhoptry protein 18 (rop18) dna vaccine protective immunity
Online-Zugang:	https://www.parasite-journal.org/articles/parasite/full_html/2020/01/parasite190121/parasite190121.html
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