PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis

Abstract Protein arginine methyltransferase 1 (PRMT1) is able to promote breast cancer cell proliferation. However, the detailed mechanisms of PRMT1-mediated breast cancer cell proliferation are largely unknown. In this study, we reveal that PRMT1-mediated methylation of EZH2 at the R342 site (meR34...

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Detalhes bibliográficos

Principais autores:	Zhongwei Li, Diandian Wang, Xintian Chen, Wenwen Wang, Pengfei Wang, Pingfu Hou, Minle Li, Sufang Chu, Shuxi Qiao, Junnian Zheng, Jin Bai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2021-11-01
coleção:	Cell Death and Disease
Acesso em linha:	https://doi.org/10.1038/s41419-021-04381-5
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