Progranulin regulation of autophagy contributes to its chondroprotective effect in osteoarthritis

Progranulin (PGRN) is a multifunctional growth factor involved in many physiological processes and disease states. The apparent protective role of PGRN and the importance of chondrocyte autophagic function in the progression of osteoarthritis (OA) led us to investigate the role of PGRN in the regula...

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Detalhes bibliográficos

Principais autores:	Yiming Pan, Yuyou Yang, Mengtian Fan, Cheng Chen, Rong Jiang, Li Liang, Menglin Xian, Biao Kuang, Nana Geng, Naibo Feng, Lin Deng, Wei Zheng, Fengmei Zhang, Xiaoli Li, Fengjin Guo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	KeAi Communications Co., Ltd. 2023-07-01
coleção:	Genes and Diseases
Assuntos:	Anabolism ATG12 ATG5 Autophagy Catabolism Osteoarthritis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352304222001660
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