IRE1α regulates the PTHrP-IHH feedback loop to orchestrate chondrocyte hypertrophy and cartilage mineralization

Cartilage development is controlled by the highly synergistic proliferation and differentiation of growth plate chondrocytes, in which the Indian hedgehog (IHH) and parathyroid hormone-related protein-parathyroid hormone-1 receptor (PTHrP-PTH1R) feedback loop is crucial. The inositol-requiring enzym...

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Detalhes bibliográficos

Principais autores:	Mengtian Fan, Nana Geng, Xingyue Li, Danyang Yin, Yuyou Yang, Rong Jiang, Cheng Chen, Naibo Feng, Li Liang, Xiaoli Li, Fengtao Luo, Huabing Qi, Qiaoyan Tan, Yangli Xie, Fengjin Guo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	KeAi Communications Co., Ltd. 2024-01-01
coleção:	Genes and Diseases
Assuntos:	Cartilage development ER stress ERN1 IHH PTHrP/PTH1R
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352304222003221
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