Distinct and overlapping roles of MutLγ, Mus81-Mms4, and STR in meiotic Holliday junction processing
Abstract Most meiotic crossovers arise from the nucleolytic resolution of recombination intermediates that ZMM proteins stabilize as double Holliday junctions (dHJs). MutLγ is the nuclease thought to resolve these ZMM-bound dHJs into crossovers, but alternative enzymes - including Mus81-Mms4 and the...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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Nature Portfolio
2026-06-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-026-73888-2 |
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