The mechanism of electroacupuncture-mediated improvement in Parkinson’s disease by inhibiting ferroptosis through activating the Nrf2/GPX4 signal pathway

IntroductionFerroptosis, an iron-dependent regulated cell death pathway, shares several features of Parkinson’s disease (PD) physiopathology, and efficient neuroprotective therapies are required to prevent DAergic neuron death initiated by ferroptosis. Electroacupuncture (EA), a treasure of Traditio...

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Главные авторы:	Min Wang, He-Sheng Zheng, Wei-Liang Ye, Jin-Dong Mao, Kun Zhang, Le Yang, Ming-Gao Zhao, Shui-Bing Liu, Rui Liu, Yu-Mei Wu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2025-05-01
Серии:	Frontiers in Aging Neuroscience
Предметы:	Parkinson’s disease ferroptosis electroacupuncture nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 substantia nigra
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fnagi.2025.1551404/full
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