Sestrin2 ameliorates LPS-induced cardiomyocyte injury by inhibiting ferroptosis via the Nrf2/HO-1 pathway
Abstract Background The pathogenesis of sepsis-induced myocardial injury is complex. Currently, treatment for this disease remains suboptimal. Sestrin2 (Sesn2) is an antioxidant protein and has been shown to have a protective role in some diseases. However, its role in sepsis-induced cardiomyocyte i...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2025-11-01
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| Col·lecció: | European Journal of Medical Research |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s40001-025-03580-6 |
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