Antioxidants Threaten Multikinase Inhibitor Efficacy against Liver Cancer by Blocking Mitochondrial Reactive Oxygen Species

Sorafenib and regorafenib, multikinase inhibitors (MKIs) used as standard chemotherapeutic agents for hepatocellular carcinoma (HCC), generate reactive oxygen species (ROS) during cancer treatment. Antioxidant supplements are becoming popular additions to our diet, particularly glutathione derivativ...

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Detalhes bibliográficos

Principais autores:	Blanca Cucarull, Anna Tutusaus, Tania Hernáez-Alsina, Pablo García de Frutos, María Reig, Anna Colell, Montserrat Marí, Albert Morales
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-08-01
Colecção:	Antioxidants
Assuntos:	chemotherapy oxidative stress glutathione superoxide BCL-2 hepatocellular carcinoma
Acesso em linha:	https://www.mdpi.com/2076-3921/10/9/1336
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