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The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent.

Streptococcus pneumoniae is the world's leading cause of pneumonia, bacteremia, meningitis and otitis media. A major pneumococcal virulence factor is the cholesterol-dependent cytolysin, which has the defining property of forming pores in cholesterol-containing membranes. In recent times a clinicall...

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Principais autores: Richard M Harvey, Catherine E Hughes, Adrienne W Paton, Claudia Trappetti, Rodney K Tweten, James C Paton
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2014-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC4126675?pdf=render
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