Clonorchis sinensis-driven hepatocarcinogenesis via E2F1-CD24 transcriptional axis: mechanistic and therapeutic implications

Abstract Background Hepatocellular carcinoma (HCC) remains a global health burden, with disproportionately high mortality in China’s Guangxi region, where endemic Clonorchis sinensis (C. sinensis) infection coincides with elevated HCC incidence. Preliminary single-cell sequencing revealed marked ove...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Wen-Min Lu, Jin Yan, Zhao-Ji Liu, Yong Wu, Qian-Ru Cui, Ji Feng, Yu Chen, Guang-Zhi Zhu, Tao Peng, Jing Zhou, Guo-Dong Lu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-08-01
Цуврал:	Parasites & Vectors
Нөхцлүүд:	Hepatocellular carcinoma Clonorchis sinensis CD24 E2F1 Tumor promotion
Онлайн хандалт:	https://doi.org/10.1186/s13071-025-06979-6
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!