Limosilactobacillus reuteri metabolites modulate immune pathways and intestinal barrier repair after 5 fluorouracil exposure

Abstract Antimetabolites such as 5 fluorouracil are known to induce inflammation in the gut and oral cavity, underscoring the need for strategies that mitigate chemotherapy-associated toxicity. The aim of this study was to determine whether secreted components from the probiotic bacterium Limosilact...

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Bibliografiska uppgifter

Huvudupphov:	Gintare Lasaviciute, Marta López Plana, Sofia Sundberg Örtegren, Sevasteia Telli, Symeon Kourmoulakis, Ludwig Ermann Lundberg, Kenny Lidberg, Oshadi Peiris, Indranil Sinha, Ann-Beth Jonsson, Stefan Roos, Anna Nilsson, Manuel Mata Forsberg, Eva Sverremark-Ekström
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Nature Portfolio 2026-04-01
Serie:	Scientific Reports
Ämnen:	Chemotherapy Probiotics Limosilactobacillus reuteri Exopolysaccharides Extracellular membrane vesicles Epithelial cells integrity
Länkar:	https://doi.org/10.1038/s41598-026-45524-y
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