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Limosilactobacillus reuteri metabolites modulate immune pathways and intestinal barrier repair after 5 fluorouracil exposure

Abstract Antimetabolites such as 5 fluorouracil are known to induce inflammation in the gut and oral cavity, underscoring the need for strategies that mitigate chemotherapy-associated toxicity. The aim of this study was to determine whether secreted components from the probiotic bacterium Limosilact...

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Hlavní autoři: Gintare Lasaviciute, Marta López Plana, Sofia Sundberg Örtegren, Sevasteia Telli, Symeon Kourmoulakis, Ludwig Ermann Lundberg, Kenny Lidberg, Oshadi Peiris, Indranil Sinha, Ann-Beth Jonsson, Stefan Roos, Anna Nilsson, Manuel Mata Forsberg, Eva Sverremark-Ekström
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-04-01
Edice:Scientific Reports
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On-line přístup:https://doi.org/10.1038/s41598-026-45524-y
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