Time-resolved analysis of transcription kinetics in single live mammalian cells

In eukaryotic cells, RNA polymerase II synthesizes mRNA in three stages, initiation, elongation, and termination, and numerous factors determine how quickly a gene is transcribed to produce mRNA molecules through these steps. However, there are few techniques available to measure the rate of each st...

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Bibliografiske detaljer

Principais autores:	Hongyoung Choi, Byung Hun Lee, Hye Yoon Park
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2022-11-01
Serier:	Frontiers in Physics
Fag:	transcription live-cell imaging single-cell analysis transcription elongation transcription termination
Online adgang:	https://www.frontiersin.org/articles/10.3389/fphy.2022.977125/full
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