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Time-resolved analysis of transcription kinetics in single live mammalian cells

In eukaryotic cells, RNA polymerase II synthesizes mRNA in three stages, initiation, elongation, and termination, and numerous factors determine how quickly a gene is transcribed to produce mRNA molecules through these steps. However, there are few techniques available to measure the rate of each st...

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Hlavní autoři: Hongyoung Choi, Byung Hun Lee, Hye Yoon Park
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-11-01
Edice:Frontiers in Physics
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fphy.2022.977125/full
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