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Exploring MSC and HSPC interactions: new frontiers in hematopoiesis and transplant medicine

Abstract Mesenchymal stromal cells (MSCs) play a critical role in supporting hematopoietic stem and progenitor cells (HSPCs) within the bone marrow (BM) niche by providing a specialized extracellular matrix and essential signaling cues. Through the secretion of key ECM proteins and cell adhesion mol...

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Bibliografische gegevens
Hoofdauteurs: Sevanthy Suresh, Vigneshwaran Venkatesan, Saravanabhavan Thangavel, Srujan Marepally
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2025-11-01
Reeks:Stem Cell Research & Therapy
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Online toegang:https://doi.org/10.1186/s13287-025-04753-0
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