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Unravelling inclusion body myositis using a patient‐derived fibroblast model

Abstract Background Inclusion body myositis (IBM) is an inflammatory myopathy clinically characterized by proximal and distal muscle weakness, with inflammatory infiltrates, rimmed vacuoles and mitochondrial changes in muscle histopathology. There is scarce knowledge on IBM aetiology, and non‐establ...

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Principais autores: Judith Cantó‐Santos, Laura Valls‐Roca, Ester Tobías, Francesc Josep García‐García, Mariona Guitart‐Mampel, Anna Esteve‐Codina, Beatriz Martín‐Mur, Mercedes Casado, Rafael Artuch, Estel Solsona‐Vilarrasa, José Carlos Fernandez‐Checa, Carmen García‐Ruiz, Carles Rentero, Carlos Enrich, Pedro J. Moreno‐Lozano, José César Milisenda, Francesc Cardellach, Josep M. Grau‐Junyent, Glòria Garrabou
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2023-04-01
Serier:Journal of Cachexia, Sarcopenia and Muscle
Fag:
Inclusion body myositis
Myopathy
Fibroblasts
Autophagy
Inflammation
Mitochondria
Online adgang:https://doi.org/10.1002/jcsm.13178
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