Large language model-guided CAR-T in silico platform for cytokine optimization in liver cancer with low antigen density
Abstract CAR-T cell therapy has shown remarkable success in hematologic malignancies but remains limited in solid tumors such as liver cancer due to antigen heterogeneity, low target antigen density, and an immunosuppressive tumor microenvironment (TME). Cytokine engineering can enhance CAR-T persis...
Збережено в:
| Автори: | , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2026-07-01
|
| Серія: | Journal of Hematology & Oncology |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s13045-026-01822-6 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|