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Distinct blood transcriptomic profiling underlying asthma establishment and exacerbation

Background: Non-Hispanic Black individuals are disproportionately affected by asthma and severe asthma exacerbations. To elucidate asthma pathogenesis, it is essential to understand the dysregulated gene expression patterns linked to asthma status. Objective: We sought to characterize whole blood ge...

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Hlavní autoři: Baojun Wu, PhD, Mao Yang, MS, Donglei Hu, PhD, Samantha Hochstadt, MS, Bo Hyun Lee, PhD, David E. Lanfear, MD, MS, Jonathan Witonsky, MD, MAS, Paul Stemmer, PhD, Esteban G. Burchard, MD, MPH, Elad Ziv, MD, L. Keoki Williams, MD, MPH, MBA
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2026-03-01
Edice:Journal of Allergy and Clinical Immunology: Global
Témata:
Gene expression profiling
controlled asthma
uncontrolled asthma
asthma exacerbation
non-Hispanic Black
driver genes
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2772829326000068
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