One-Pot Multicomponent Synthesis of Methoxybenzo[<i>h</i>]quinoline-3-carbonitrile Derivatives; Anti-Chagas, X-ray, and In Silico ADME/Tox Profiling Studies

Several methoxybenzo[<i>h</i>]quinoline-3-carbonitrile analogs were designed and synthesized in a repositioning approach to developing compounds with anti-prostate cancer and anti-Chagas disease properties. The compounds were synthesized through a sequential multicomponent reaction of aromatic aldeh...

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Bibliografische Detailangaben

Hauptverfasser:	Hegira Ramírez, Katiuska Charris, Esteban Fernandez-Moreira, Benjamín Nogueda-Torres, Mario V. Capparelli, Jorge Ángel, Jaime Charris
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-11-01
Schriftenreihe:	Molecules
Schlagworte:	cancer chagas one-pot synthesis methoxybenzo[<i>h</i>]quinoline
Online-Zugang:	https://www.mdpi.com/1420-3049/26/22/6977
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