Structure–Activity Relationship Studies in a Series of Xanthine Inhibitors of SLACK Potassium Channels
Gain-of-function mutations in the <i>KCNT1</i> gene, which encodes the sodium-activated potassium channel known as SLACK, are associated with the rare but devastating developmental and epileptic encephalopathy known as epilepsy of infancy with migrating focal seizures (EIMFS). The design of small mo...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2024-05-01
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| coleção: | Molecules |
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| Acesso em linha: | https://www.mdpi.com/1420-3049/29/11/2437 |
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