iPSC-derived microglia: Decoding roles and therapeutic opportunities in neurodegenerative diseases
Microglia originate from erythro-myeloid progenitors (EMPs) in the early embryonic yolk sac and migrate into the developing brain, where they differentiate and mature under the regulation of chemokines, cytokines, and growth factors. As resident immune cells in the central nervous system (CNS), micr...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2026-04-01
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| coleção: | Brain Research Bulletin |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S0361923026000651 |
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