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iPSC-derived microglia: Decoding roles and therapeutic opportunities in neurodegenerative diseases

Microglia originate from erythro-myeloid progenitors (EMPs) in the early embryonic yolk sac and migrate into the developing brain, where they differentiate and mature under the regulation of chemokines, cytokines, and growth factors. As resident immune cells in the central nervous system (CNS), micr...

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Autors principals: Didi Shan, Hongxu Wang, Jianing Li, Yao Tang, Zexin Zhan, Chuanzhu Yan, Jingwen Xu, Fuchen Liu
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2026-04-01
Col·lecció:Brain Research Bulletin
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S0361923026000651
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