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A modular degron library for synthetic circuits in mammalian cells

One method of controlling protein degradation is through the use of degrons. Here the authors present a toolbox of characterised degrons as a library to fine-tune biological gene-expression systems. Its application is demonstrated by a set of tunable synthetic pulse generators in mammalian cells.

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Detaylı Bibliyografya
Asıl Yazarlar: Hélène Chassin, Marius Müller, Marcel Tigges, Leo Scheller, Moritz Lang, Martin Fussenegger
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Portfolio 2019-05-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/s41467-019-09974-5
Etiketler: Etiketle
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