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Vascular smooth muscle cell RNA-binding protein U2AF2 induces copper death by regulating C1qbp expression, delaying development of atherosclerosise

Abstract Background Atherosclerosis (AS) is the main pathological basis of atherosclerosis-related cardiovascular and cerebrovascular diseases. The phenotypic conversion and death mechanisms of vascular smooth muscle cells (VSMCs) are crucial during its development. This study reveals the molecular...

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Principais autores: Yang Yang, Hongxu Chen, Qijun Yu, Qihui Chen, Xinyue Zhou, Shanshan Zhou, Tingjiao Liu, Jinghan Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-01-01
coleção:Biological Research
Assuntos:
Atherosclerosis
Vascular smooth muscle cells
Copper death
U2AF2
C1qbp
Acesso em linha:https://doi.org/10.1186/s40659-026-00672-3
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