Vascular smooth muscle cell RNA-binding protein U2AF2 induces copper death by regulating C1qbp expression, delaying development of atherosclerosise

Abstract Background Atherosclerosis (AS) is the main pathological basis of atherosclerosis-related cardiovascular and cerebrovascular diseases. The phenotypic conversion and death mechanisms of vascular smooth muscle cells (VSMCs) are crucial during its development. This study reveals the molecular...

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Autors principals:	Yang Yang, Hongxu Chen, Qijun Yu, Qihui Chen, Xinyue Zhou, Shanshan Zhou, Tingjiao Liu, Jinghan Lin
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-01-01
Col·lecció:	Biological Research
Matèries:	Atherosclerosis Vascular smooth muscle cells Copper death U2AF2 C1qbp
Accés en línia:	https://doi.org/10.1186/s40659-026-00672-3
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