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Experimental and thermodynamic modeling of sumatriptan solubility in supercritical carbon dioxide for green pharmaceutical applications

Abstract This study examined the solubility of sumatriptan when dissolved in supercritical carbon dioxide. The temperature of the system was varied between 308 and 338 K, and the pressure was ranged between 10 and 30 MPa. The experimental mole fraction and the solubility ranged from 4.30 × 10−6 to 5...

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Autor principal: Saud Bawazeer
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2025-10-01
Colección:Scientific Reports
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Acceso en línea:https://doi.org/10.1038/s41598-025-20442-7
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