Determination of Regorafenib monohydrate (colorectal anticancer drug) solubility in supercritical CO2: Experimental and thermodynamic modeling

In this study, the solubilities of Regorafenib monohydrate (REG), a widely used as a colorectal anticancer drug, in supercritical carbon dioxide (ScCO2) were measured under various pressures and temperature conditions, for the first time. The minimum value of REG in mole fraction was determined to b...

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Hlavní autoři:	Gholamhossein Sodeifian, Ratna Surya Alwi, Fatemeh Sodeifian, Solmaz Amraee, Mohammadreza Rashidi-Nooshabadi, Fariba Razmimanesh
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-04-01
Edice:	Heliyon
Témata:	Regorafenib monohydrate Supercritical carbon dioxide Solubility Anticancer Thermodynamic modeling
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2405844024050801
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