Ligands binding diffusively to protein target act as inhibitors of protein-protein interactions.

Nuclear localization signal (NLS) sequence from capsid protein of Venezuelan equine encephalitis virus (VEEV) binds to importin-α transport protein and clogs nuclear import. Prevention of viral NLS binding to importin-α may represent a viable therapeutic route. Here, we investigate the molecular mec...

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Manylion Llyfryddiaeth

Prif Awduron:	William Jeffries, Bryan M Delfing, Xavier E Laracuente, Xingyu Luo, Audrey Olson, Kenneth W Foreman, Kyung Hyeon Lee, Greg Petruncio, Vito De Benedictis, Mikell Paige, Kylene Kehn-Hall, Christopher Lockhart, Dmitri K Klimov
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Public Library of Science (PLoS) 2025-09-01
Cyfres:	PLoS Computational Biology
Mynediad Ar-lein:	https://doi.org/10.1371/journal.pcbi.1013495
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!