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Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis

Hormone-sensitive lipase (HSL) regulates the hydrolysis of acylglycerol and cholesteryl ester (CE) in various organs, including adipose tissues. However, the hepatic expression level of HSL has been reported to be almost negligible. In the present study, we found that mice lacking both leptin and HS...

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Principais autores: Motohiro Sekiya, Jun-ichi Osuga, Naoya Yahagi, Hiroaki Okazaki, Yoshiaki Tamura, Masaki Igarashi, Satoru Takase, Kenji Harada, Sachiko Okazaki, Yoko Iizuka, Ken Ohashi, Hiroaki Yagyu, Mitsuyo Okazaki, Takanari Gotoda, Ryozo Nagai, Takashi Kadowaki, Hitoshi Shimano, Nobuhiro Yamada, Shun Ishibashi
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2008-08-01
Serier:Journal of Lipid Research
Fag:
fatty liver
leptin
mouse
lipoproteins
ob/ob
hepatocytes
Online adgang:http://www.sciencedirect.com/science/article/pii/S0022227520347015
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