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Revisiting the clastosome: a stress-induced nuclear proteolytic compartment of mammalian cells

The nuclear ubiquitin proteasome system (UPS) is fundamental to maintaining proteostasis and ensuring the quality control of nuclear proteins. Within the nucleus, proteasomes are distributed throughout the nucleoplasm and can aggregate into nuclear bodies. In 2002, our group provided the first descr...

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Hauptverfasser: Miguel Lafarga, María T. Berciano, Noemí Rueda, Sofía Cardona-Cortés, Olga Tapia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-06-01
Schriftenreihe:Frontiers in Neuroanatomy
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fnana.2026.1839944/full
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