Generation of a H9 Clonal Cell Line With Inducible Expression of NUP98-KDM5A Fusion Gene in the AAVS1 Safe Harbor Locus

Pediatric acute myeloid leukemia (AML) is a rare and heterogeneous disease that remains the major cause of mortality in children with leukemia. To improve the outcome of pediatric AML we need to gain knowledge on the biological bases of this disease. NUP98-KDM5A (NK5A) fusion protein is present in a...

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Autores principales:	Joan Domingo-Reinés, Gonzalo Martínez-Navajas, Rosa Montes, Mar Lamolda, Iris Simón, Julio Castaño, Rosa Ríos-Pelegrina, Javier Luis Lopez-Hidalgo, Raimundo García del Moral, Juan A. Marchal, Pedro J. Real, Verónica Ramos-Mejía
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2022-06-01
Colección:	Frontiers in Cell and Developmental Biology
Materias:	acute myeliod leukemia pediatric disease model human stem cell hematopoieisis
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fcell.2022.846092/full
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