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Peripheral Leukocytosis Is Inversely Correlated with Intratumoral CD8+ T-Cell Infiltration and Associated with Worse Outcome after Chemoradiotherapy in Anal Cancer

Peripheral blood leukocytosis has been implicated in promoting tumor progression leading to worse survival, but the mechanisms behind this phenomenon remain unexplored. Here, we examined the prognostic role of pretreatment white blood cell (WBC) count and clinicopathologic parameters in the context...

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Autores principales: Daniel Martin, Franz Rödel, Ria Winkelmann, Panagiotis Balermpas, Claus Rödel, Emmanouil Fokas
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017-09-01
Colección:Frontiers in Immunology
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Acceso en línea:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01225/full
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