Peripheral Leukocytosis Is Inversely Correlated with Intratumoral CD8+ T-Cell Infiltration and Associated with Worse Outcome after Chemoradiotherapy in Anal Cancer

Peripheral blood leukocytosis has been implicated in promoting tumor progression leading to worse survival, but the mechanisms behind this phenomenon remain unexplored. Here, we examined the prognostic role of pretreatment white blood cell (WBC) count and clinicopathologic parameters in the context...

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Bibliografiske detaljer

Principais autores:	Daniel Martin, Franz Rödel, Ria Winkelmann, Panagiotis Balermpas, Claus Rödel, Emmanouil Fokas
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2017-09-01
Serier:	Frontiers in Immunology
Fag:	anal cancer leukocytosis immune microenvironment tumor-infiltrating-lymphocytes neutrophils CD8
Online adgang:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01225/full
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