Racial heterogeneity of IgA1 hinge-region O-glycoforms in patients with IgA nephropathy

Summary: Galactose (Gal)-deficient IgA1 (Gd-IgA1) is involved in IgA nephropathy (IgAN) pathogenesis. To reflect racial differences in clinical characteristics, we assessed disease- and race-specific heterogeneity in the O-glycosylation of the IgA1 hinge region (HR). We determined serum Gd-IgA1 leve...

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Detalhes bibliográficos

Principais autores:	Yukako Ohyama, Hisateru Yamaguchi, Soshiro Ogata, Samantha Chiurlia, Sharon N. Cox, Nikoletta-Maria Kouri, Maria J. Stangou, Kazuki Nakajima, Hiroki Hayashi, Daijo Inaguma, Midori Hasegawa, Yukio Yuzawa, Naotake Tsuboi, Matthew B. Renfrow, Jan Novak, Aikaterini A. Papagianni, Francesco P. Schena, Kazuo Takahashi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-11-01
coleção:	iScience
Assuntos:	Clinical finding Physiological state Pathophysiology
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S258900422201495X
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