Racial heterogeneity of IgA1 hinge-region O-glycoforms in patients with IgA nephropathy

Summary: Galactose (Gal)-deficient IgA1 (Gd-IgA1) is involved in IgA nephropathy (IgAN) pathogenesis. To reflect racial differences in clinical characteristics, we assessed disease- and race-specific heterogeneity in the O-glycosylation of the IgA1 hinge region (HR). We determined serum Gd-IgA1 leve...

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Auteurs principaux:	Yukako Ohyama, Hisateru Yamaguchi, Soshiro Ogata, Samantha Chiurlia, Sharon N. Cox, Nikoletta-Maria Kouri, Maria J. Stangou, Kazuki Nakajima, Hiroki Hayashi, Daijo Inaguma, Midori Hasegawa, Yukio Yuzawa, Naotake Tsuboi, Matthew B. Renfrow, Jan Novak, Aikaterini A. Papagianni, Francesco P. Schena, Kazuo Takahashi
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2022-11-01
Collection:	iScience
Sujets:	Clinical finding Physiological state Pathophysiology
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S258900422201495X
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