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Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions

The Nerve Growth Factor (NGF) neurotrophin acts in the maintenance and growth of neuronal populations. Despite the detailed knowledge of NGF’s role in neuron physiology, the structural and mechanistic determinants of NGF bioactivity modulated by essential endogenous ligands are still lacking. We pre...

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Huvudupphov: Francesca Paoletti, Franci Merzel, Alberto Cassetta, Iza Ogris, Sonia Covaceuszach, Jože Grdadolnik, Doriano Lamba, Simona Golič Grdadolnik
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Association for the Advancement of Science (AAAS) 2021-01-01
Serie:Computational and Structural Biotechnology Journal
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Länkar:http://www.sciencedirect.com/science/article/pii/S2001037021001902
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