Meiotic prophase length modulates Tel1-dependent DNA double-strand break interference.
During meiosis, genetic recombination is initiated by the formation of many DNA double-strand breaks (DSBs) catalysed by the evolutionarily conserved topoisomerase-like enzyme, Spo11, in preferred genomic sites known as hotspots. DSB formation activates the Tel1/ATM DNA damage responsive (DDR) kinas...
Salvato in:
| Autori principali: | , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2024-03-01
|
| Serie: | PLoS Genetics |
| Accesso online: | https://doi.org/10.1371/journal.pgen.1011140 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|