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Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1.

<h4>Background</h4>Members of the Mps1 kinase family play an essential and evolutionarily conserved role in the spindle assembly checkpoint (SAC), a surveillance mechanism that ensures accurate chromosome segregation during mitosis. Human Mps1 (hMps1) is highly phosphorylated during mitosis and many...

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Hlavní autoři: Zhen Dou, Conrad von Schubert, Roman Körner, Anna Santamaria, Sabine Elowe, Erich A Nigg
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2011-04-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0018793
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