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Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin–Matrix-M® nanoparticle vaccine induces neutralizing responses in nonhuman primates

Abstract With the recent rise in cases of highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b infection in humans and animals, there is an associated increase in the risk of human-to-human transmission. In this study, we characterize a recombinant A(H5N1) A/American Wigeon/South Carolina...

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Auteurs principaux: Nita Patel, Asma Rehman, Jessica F. Trost, Rhonda Flores, Zach Longacre, Mimi Guebre-Xabier, Haixia Zhou, Bin Zhou, Kelsey Jacobson, Desheng Jiang, Xiaoyun Bai, Rafia Khatoon, Thomas Kort, James Norton, M. Madhangi, Melinda Hersey, Ann M. Greene, Filip Dubovsky, Gale Smith
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2025-07-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-025-61964-y
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