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Population immunity to clade 2.3.4.4b H5N1 is dominated by anti-neuraminidase antibodies

ABSTRACT Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses continue to expand geographically and across mammalian hosts, raising concern about pandemic potential. The degree and specificity of pre-existing immunity in humans are key determinants of this risk. We analyzed hemagglutinin...

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Principais autores: Gagandeep Singh, Disha Bhavsar, Enikö Hermann, Charles Gleason, Harkirat Singh Sandhu, Parul Singh, Jessica R. Nardulli, Neko Lyttle, Yuexing Chen, Suzana Sabaiduc, Garazi Peña Alzua, Danuta M. Skowronski, Viviana Simon, Florian Krammer
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2026-05-01
Serier:mBio
Fag:
H5N1
H5N5
D1.1
B3.13
avian influenza
neuraminidase
Online adgang:https://journals.asm.org/doi/10.1128/mbio.00445-26
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