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Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages

Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that utilizes its type III secretion systems (T3SSs) to inject virulence factors into host cells and colonize the host. In turn, a subset of cytosolic immune receptors respond to T3SS ligands by forming multimeric signal...

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Bibliographic Details
Main Authors: Marisa S Egan, Emily A O'Rourke, Shrawan Kumar Mageswaran, Biao Zuo, Inna Martynyuk, Tabitha Demissie, Emma N Hunter, Antonia R Bass, Yi-Wei Chang, Igor E Brodsky, Sunny Shin
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications Ltd 2025-03-01
Series:eLife
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Online Access:https://elifesciences.org/articles/90107
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