Involvement of the Eukaryote-Like Kinase-Phosphatase System and a Protein That Interacts with Penicillin-Binding Protein 5 in Emergence of Cephalosporin Resistance in Cephalosporin-Sensitive Class A Penicillin-Binding Protein Mutants in <named-content content-type="genus-species">Enterococcus faecium</named-content>

ABSTRACT The intrinsic resistance of Enterococcus faecium to ceftriaxone and cefepime (here referred to as “cephalosporins”) is reliant on the presence of class A penicillin-binding proteins (Pbps) PbpF and PonA. Mutants lacking these Pbps exhibit cephalosporin susceptibility that is reversible by e...

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Autors principals:	Charlene Desbonnet, Amelia Tait-Kamradt, Monica Garcia-Solache, Paul Dunman, Jeffrey Coleman, Michel Arthur, Louis B. Rice
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2016-05-01
Col·lecció:	mBio
Accés en línia:	https://journals.asm.org/doi/10.1128/mBio.02188-15
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