Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains

ABSTRACT Resistance to ampicillin and imipenem in Enterococcus faecalis is infrequent. However, the evolution of resistance can occur through prolonged antibiotic exposure during the treatment of chronic infections. In this study, we conducted a long-term evolution experiment using four genetically...

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Principais autores:	Paul Ugalde Silva, Charlene Desbonnet, Louis B. Rice, Mónica García-Solache
格式:	Artigo
语言:	Inglês
出版:	American Society for Microbiology 2024-12-01
丛编:	mBio
主题:	Enterococcus beta-lactams drug resistance evolution antibiotic dependence c-di-AMP long-term evolution experiment
在线阅读:	https://journals.asm.org/doi/10.1128/mbio.02897-24
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