Design, synthesis, in-silico, and in-vitro assessment of pyrazolone-merged chalcone derivatives as anti-alzheimer agents
Novel anti-cholinesterase inhibitors including pyrazolone merging chalcone derivatives have been developed and molecular docking has been performed. From the docking results, compound 48 (-8.3 k/cal) shows the highest binding affinity toward the AChE enzyme compared to the standard drug donepezil (-...
Furkejuvvon:
| Váldodahkkit: | , , |
|---|---|
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
2025-12-01
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| Ráidu: | Brazilian Journal of Pharmaceutical Sciences |
| Fáttát: | |
| Liŋkkat: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502025000100349&lng=en&tlng=en |
| Fáddágilkorat: |
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