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Exploring the multifaceted Dbf4-dependent kinase from temporal, spatial, and substrate repertoire perspectives

Abstract The Dbf4‑dependent kinase (DDK), composed of the catalytic subunit Cdc7 and the regulatory subunit Dbf4, is a serine/threonine kinase traditionally defined as an essential activator of DNA replication. Here, we review DDK function from three complementary perspectives: its temporal regulati...

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書誌詳細
主要な著者: Lorenzo Galanti, Boris Pfander
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2026-06-01
シリーズ:Communications Biology
オンライン・アクセス:https://doi.org/10.1038/s42003-026-10512-5
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