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Engineering extracellular vesicles to deliver CRISPR ribonucleoprotein for gene editing

Abstract Clustered regularly interspaced palindromic repeats (CRISPR) is a gene editing tool with tremendous therapeutic potential. Recently, ribonucleoprotein (RNP) complex‐based CRISPR systems have gained momentum due to their reduction of off‐target editing. This has coincided with the emergence...

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Principais autores: Joseph Andrew Whitley, Houjian Cai
פורמט: Artigo
שפה:Inglês
יצא לאור: Wiley 2023-09-01
סדרה:Journal of Extracellular Vesicles
נושאים:
Cas9/sgRNA ribonucleoprotein
CRISPR
delivery
encapsulation
extracellular vesicles
tropism
גישה מקוונת:https://doi.org/10.1002/jev2.12343
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